THC vs CBD Oil – The Ultimate Guide!


Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the two significant cannabinoids that naturally occur in cannabis, or the cannabis sativa plant. Both the substances talk with the human brain and the body's cannabinoid receptors. However, their effects on the body and mind are quite distinct. 

CBD is essentially non-psychoactive, meaning it would not stone the user. Due to this, CBD shows up more frequently in natural and dietary supplements compared to THC. In this THC vs CBD oil article, we'll dig deeper and look at these critical compounds much closer to understand why these cannabinoids are being used the way they are.

How THC Was Discovered


Raphael Mechoulam

This story is quite impressive and entertaining. THC was initially discovered in a laboratory not that long ago in 1940 by Raphael Mechoulam, an Israeli researcher. After the compound was isolated, Mechoulam took some of them home and ingested it orally with friends after making a cake out of the compound, thereby establishing the theory that the substance was a cannabis compound that makes the user stoned when administered in certain amounts.

Mechoulam and his close-knit research team led the cannabis research pathway for long after that. They later found the natural endocannabinoid system of the body, which comprised naturally occurring cannabinoid receptors and compounds found in various regions of the human body.

Sadly the medicinal effects of CBD Oil were missed out on for far too long since due to THC's mind-altering traits, the whole cannabis family has come under the scanner of law enforcers. The Controlled Substance Act (1970) and legislation of the Nixon era created the guidelines on how controlled substances would be defined and enforced by the FDA and DEA.

Is THC and CBD Oil Legal?

Most people know that THC is the compound that alters the mind and is why most people smoke weed, the first controlled substance's definition had no such distinction to its credit. Therefore, all cannabis strains were ruled out as illegal in America at both the state and federal level, irrespective of the THC level the plant comprised.

This list had cannabis sativa L. or industrial hemp, which is a strain of cannabis whose levels of THC are so low that one must consume it in considerable quantities to get anywhere close to "high". The plant has come under the scanner of the recent legislation, since Congress, coming under public pressure, has been making efforts to lift the industrial hemp prohibition, thereby helping American farmers grow and sell the crop legally and in large quantities.

What caused public opinion on industrial hemp shift so much in the last 10 years? Mostly, it's due to the growing evidence of the pro-health traits of CBD, another cannabinoid that's found in cannabis. We have covered the legal status of CBD Oil in all 50 US states here on CBDOilPolice.

Even More Research On CBD

Cannabidiol's isolation was also done in 1940 by Raphael Mechoulam the guy we wrote about earlier. Usually, it's the most commonly found cannabinoid in cannabis plants, with a significant amount of scientific research done on it.

The compound is non-psychoactive making it legal. This means it will not affect people's ability to concentrate or not make them high. It is considered to moderate THC's psychoactive traits when both are used in conjunction. CBD does this by counteracting the cognitive effects of THC.

CBD's therapeutic effects could include:

  • Pain reduction 
  • Management of mental health disorders
  • Travel Sickness
  • Anti-convulsant traits
  • Cardiovascular health
  • Digestive issues like IBS and Ulcerative Colitis 
  • Better sleep
  • Beautiful Skin
  • Helping Smokers Quit

How is THC different from CBD?

So far in 2019, research into the multiple effects of cannabinoids is progressing, one thing can be said for sure that CBD won't stone you, unlike THC. This is maybe the most significant difference between the two substances, and which is for the following two reasons in my opinion.

Many people want easy access to CBD for its pro-health traits and do not want to put up with the cognitive impairment of medical marijuana THC causes.

Also, this must concern regulatory agencies who do not want people to get high as that turns out to be the drug enforcement agencies' top priority, even when patients are using CBD oil to treat severe and chronic medical conditions in children like in the case of Charlotte from Charlottes Webb Hemp.

CBD-related products are on the rise and marijuana's legalization (for both recreational and medicinal use) are happening simultaneously. Outdated laws that were governing marijuana are finally recoiling, thanks to the flourishing research about these substances' safety and the major alterations in marijuana's public acceptance and/or growth of CBD usage.

This could be a bit perplexing for the buyer because both THC oils and CBD oils can be bought legally, based on the state the purchase is being made in. These products aren't the same as I will now explain for you.


To produce THC oil you need to extract cannabis plant cannabinoids. That is easier said than done. But the major difference is that the oil is obtained from strains produced for recreational or medicinal uses that are known for their high THC levels.

Consequently, THC oil is extremely rich in THC and would provide you with a high, irrespective of you taking it orally, sublingually, or smoking it in products made for dabbing or vaping.

But, although THC is renowned for its recreational use in states that have legalized its use, it shouldn't be misunderstood for being valuable only to recreational users. THC, in fact, also has critical medicinal usages as discussed earlier, and some individuals do use the oil for its therapeutic impact on several health conditions.


To make CBD Oil we need Industrial hemp, a kind of cannabis strain that has low levels of THC. Products sold as CBD oil must have .3% or lower THC in them. This means you're not getting high consuming the oil like you would smoking a normal joint and it remains legal in most US states.

CBD oils, in other cases, are promoted as "full spectrum". In such cases, you could expect a balanced combination of different cannabinoids that reproduce the variety of specific hemp strains the product was extracted from. These complete spectrum items almost always comprise trace quantities of THC, but not substantial enough to cause a high or the stoned look.

CBD isolate is used to make some CBD oils. This denotes the cannabinoid CBD separated from all others the plant has, resulting in a pure crystal which then gets added to various CBD products.

There are several people, which includes cannabis research experts, who believe the full spectrum oil could offer increased health advantages when consumed sensibly. This is due to the complex engagement of the several cannabinoids as they get utilized by the body and communicate with the endocannabinoid setup.

Cannabichromene (CBC)

Unlike the human understanding of other cannabinoids, CBC bonds with receptors that lie outside the endocannabinoid system of the human body.

Moreover, it supposedly has a synergistic impact on the brain and body when ingested in combination with THC, augmenting its powerful anti-viral, anti-inflammatory, antibiotic and anti-fungal traits. It could have both neurogenesis and antidepressant effects as well.

More research is needed to fully ascertain how this cannabinoid reacts with the human body's immune and nervous systems. Moreover, completely understanding its synergistic impact on other cannabinoids would open the gates for further research.

Cannabigerol (CBG)

In the growing process, cannabis plants churn out a significant amount of this cannabinoid. With the plant's maturity, however, most of the CBG gets converted to THC, CBD, or other cannabinoids. As a result, it is at times called "stem cell" cannabinoid.

It's known for binding with both the endocannabinoid receptors found in the body. Also, it could have multiple therapeutic benefits that medical research is yet to discover fully.

CBG research is still in its early stages, and there are no significant human-based clinical studies yet. But the studies have been carried out extensively on animal subjects to investigate its likely effect further as a treatment for colitis, neurodegeneration, psoriasis, cancer, digestive disorders, and several other ailments.

Cannabinol (CBN)

Cannabinol shows up in cannabis as soon as the plant-based THC starts to deteriorate in quality and integrity due to exposure to oxygen and light over a period. It's among the few cannabinoids that aren't from CBG, which is most cannabinoids' stem cell found in cannabis.

It is believed to have a robust sedative impact, with likely future applications to augment or replace highly addictive sedatives that are prescribed currently. It could also play a vital role in managing appetite and decreasing the growth of cancer tumor but further research is still needed.

The Endocannabinoid System, CBD, and THC

Both THC and CBD are compounds interacting with the endocannabinoid system of the human body. It turns out the body makes its unique cannabinoid analogs that trigger receptors found in the human body and brain, thereby controlling an array of processes. Two primary receptors located in the endocannabinoid setup, to date, have been detected.

Cannabinoid Receptor Type 1 (CB1)

Concentrated in the central nervous system, spinal cord and brain, these receptors help regulate a range of body functions, which include memory, appetite, neuroprotection, sleep, reproduction, digestion, pain and emotion. 

Cannabinoid Receptor Type 2 (CB2)

Found primarily in the nervous system (peripheral), these receptors have a significant role to play in regulating several immune system functions, such as inflammation. 

CBD vs THC: Various Modes of Action

Although both CBD and THC talk with the endocannabinoid setup, THC has a more direct interaction than CBD. THC can, in fact, directly bind to both kinds of receptors; the effects created could vary across people. This explains why different people have unique reactions to THC's effects concerning its mind-altering function. 

CBD, on the other hand, indirectly reacts by constraining the FAAH enzyme within the body. The enzyme deconstructs the vital natural cannabinoid the body makes, called anandamide. 

Anandamide has a pivotal role to play in the mood according to Mary Biles. By impeding FAAH's action to break anandamide down, CBD works to augment levels of this pertinent brain compound that boosts mood. This could be the reason why some people find CBD helping them with their anxiety and depression. 

Cannabinoid Research

It's worth noting that research that throws light on the ways various cannabinoids work together with the body's endocannabinoid system has been hampered severely by prohibition laws, making cannabis research exceedingly tricky. 

Fortunately, general awareness of this terrible scenario is on the surge, and archaic laws that have impeded research thus far are being increasingly ignored for fresh, quality analysis. Pharmaceutical firms, including GW Pharmaceuticals, are now championing the cause of substantial cannabis medical research. 


THC is illegal and can significantly impact your cognition, both in the long and short term. The effects include impaired reasoning and thinking, a decreased capacity to strategize and organize things, reduced decision-making, and reduced control over impulses. Chronic THC usage ties with significant abnormalities in the brain and heart. 

CBD doesn't share the harmful THC cognitive effects. CBD can counteract THC's psychoactive effects. Cannabis plants contain small quantities of CBD and increased amounts of THC, causing a stronger feeling of being stoned. Plants with less THC and more CBD create a more relaxed, weaker effect. 

Given the rising popularity of cannabis for its medicinal traits, breeders are currently making strains with an increased CBD-to-THC ratio to reduce the psychoactive effects on humans. Overall, the reduced health risks attached to CBD, in combination with its efficacy, make CBD a much better substance for natural applications compared to THC or any other cannabinoid.

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